Presentation- 1 strip of 10 capsule
Mechanism of action :-
Domperidone is a peripheral dopamine D2-receptor antagonist, which regulates the motility of gastric and small intestinal smooth muscle. It increases the duration of antral and duodenal contractions and also LES resting pressure, thus stimulating gastric emptying and is also effective in relief of symptoms of reflux esophagitis. Antiemetic activity is due to the blockade of dopamine receptors in the chemoreceptor trigger zone. Omeprazole inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of H+/K+ ATPase of the gastric parietal cell. It is activated at an acidic pH to a sulphenamide derivative that binds irreversibly to H+/K+ ATPase, an enzyme system found at the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with K ions) into the gastric lumen.
Indication & Dosage:- Dyspepsia, Gastro-oesophageal reflux disease Adult 1 cap bid or as directed by the physician
Presentation- 1 strip of 10 capsule
Content:-
Each Hard Gelatin Cap Contains Rabeprazole 20mg+Domperidon 30mg Sustain Release capsule Widely used combination of PPI and anti emetic for complete stomach relief. Domperidone is a peripheral dopamine D2-receptor antagonist, which regulates the motility of gastric and small intestinal smooth muscle. Thus stimulating gastric emptying and is also effective in relief of symptoms of reflux esophagitis. Antiemetic activity is due to the blockade of dopamine receptors in the chemoreceptor trigger zone.
Indication
Dosage:- One capsule once daily, preferably before evening meals
Available in Alu-Alu pack of 10 capsules